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getting tested for mycoplasma and other infectious gulf war diseases

by PH Saturday, Jul. 16, 2005 at 7:30 AM


  * * * * * * * * * * * * * * * * * * * * * * * * *

MYCOPLASMA REGISTRY for gulf war syndrome & chronic fatigue syndrome


for Mycoplasmal and Other Infections with International List of Laboratories"

© February 2005 Sean & Leslee Dudley

* * * * * * * * * * * * * * * * * * * * * * * * *

IF YOU TEST POSITIVE for mycoplasmas or other pathogens please help us by filling out our confidential on-line Mycoplasma Registry Registration & Medical Survey for patients:

Systemic Mycoplasma Infections are found in patients with: Gulf War Syndrome, Chronic Fatigue Syndrome, Myalgic Encephalomyelitis, Fibromyalgia, Lyme Disease, Rheumatoid Arthritis, Systemic Lupus Erythematosus, Scleroderma, Sjogren's Syndrome, Amyotrophic Lateral Sclerosis, Multiple Sclerosis, Cystic Fibrosis, Asthma, Respiratory Distress Syndrome, Pneumonia, Bronchitis, Inflammatory Bowel Disease, Sarcoidosis, Wegener's Disease, Kikuchi's Disease, Leukemia, Alzheimer's Disease, Autism, Infertility, Stevens-Johnson Syndrome, and Acquired Immune Deficiency Syndrome, Hypercoagulation, Heart Disease, Stroke and Cancer.

? NEW (ICD-10-CM) code for Mycoplasma Infections is: "Mycoplasma A49.3" World Health Organization (WHO) International Classification of Diseases Tenth Revision, Clinical Modification (ICD-10-CM) Chapter A - Infectious and Parasitic Diseases

* * * * * * * * * * * * * * * * * * * * * * * * *


The top three pathogens that Chronic Fatigue Syndrome and Fibromyalgia patients on the Mycoplasma Registry

test positive for using PCR blood tests:

1. Mycoplasma fermentans (incognitus strain and various other strains)

2. Human Herpes Virus-6a (HHV-6a)

3. Chlamydia pneumoniae ("Chronic Chlamydia pneumoniae infection")

Others pathogens found:


Mycoplasma pneumoniae

Mycoplasma hominis

Ureaplasma urealyticum

Mycoplasma genitalium

Mycoplasma penetrans

Borrelia burgdorferi ("Chronic Lyme Disease"

may cause or trigger fibromyalgia)

Brucellosis ("Chronic Brucellosis")

Rickettsia Diseases:

Coxiella burnetii (Q-Fever and "Post-Q Fever Fatigue Syndrome") Staphylococcus


Epstein-Bar Virus (reactivation)

Coxsackie B Viruses(1-6)("Chronic Coxsackie Infection" may cause or trigger fibromyalgia, myalgias and other diseases.)

Parvovirus B19("Chronic Parovirus Infection" may cause or trigger fibromyalgia, arthralgia, arthritis)

Enteroviruses (causes: "Chronic inflammatory muscle disease"or fibromyalgia)


Borna Disease virus

Cytocidal Viruses

Hepatitis C ("Chronic Hepatitis C" may cause or trigger fibromyalgia)

* * * * * * * * * * * * * * * * * * * * * * * * *


The Gulf War Mycoplasma Study showed that nearly all the Gulf War veterans who tested positive for mycoplasma infections were positive for Mycoplasma fermentans. Mycoplasma genitalium was also found and a very small percentage tested positive for Mycoplasma pneumoniae.

We recommend that all Gulf War veterans also get tested for: uranium poisoning from exposure to depleted uranium, antibodies to experimental vaccine adjuvants such as squalene, and if there has been any exposure to organophosphate pesticides or sarin nerve gas get tested for the blood enzyme, paraoxonase.

In addition, Veterans have experience long term side effects from prescription drugs such as:

pyridostigmine bromide, given to troops to protect against nerve gas, and the antimalarial drug Lariam (mefloquine).

* * * * * * * * * * * * * * * * * * * * * * * * *



Mycoplasma penetrans

Mycoplasma pirum

Mycoplasma fermentans (incognitus strain)

Mycoplasma fermentans (various other strains)

Mycoplasma hominis

Mycoplasma genitalium

Mycoplasma pneumoniae

Ureaplasma urealyticum


Human Immunodeficiency Virus (HIV)

Human Herpes Virus-6a (HHV-6a)


Herpes Simplex virus


* * * * * * * * * * * * * * * * * * * * * * * * *




If bitten by ticks or fleas carrying Borrelia burgdorferi you can develop traditional Lyme Disease, which is self-limiting and carried by a deer tick. Our experience with patients suggests that if the tick or flea also carries co-infections, such as Babesiosis or especially Mycoplasmas, you may develop "Chronic Lyme Disease" also known as "New Lyme Disease" as well as Chronic Fatigue Syndrome, Fibromyalgia and Autoimmune Diseases.

"Montana Lyme Disease" symptoms are similar to Lyme Disease. However, it is caused by a Lyme disease-like agent that has adapted to the Rocky Mountain wood ticks found in Montana and the Western United States.

"Chronic Lyme Disease" is a combination of the pathogen:

Lyme Disease and one or more of the following Co-infections:

Spirochetes (Borrelia bacteria):

Lyme Disease caused by three types of Spirochete Borrelia bacteria:

Borrelia burgdorferi sensu stricto (USA, UK, Europe)

Borrelia garinii (UK, Europe)

Borrelia afzelii. (UK, Europe)

Relapsing Fever caused by the spirochetes:

Borrelia hermsii

Borrelia turicatae


Mycoplasma fermentans

Mycoplasma pneumoniae

Chlamydia pneumoniae

Rickettsial Diseases:

Rocky Mountain Spotted Fever

Coxiella burnetti (Q-Fever and "Post-Q Fever Fatigue Syndrome")

Colorado Tick Fever

Eastern tick-borne Rickettsiosis


Tularemia (rabbit fever)

Ehrlichiosis (caused by Ehrlichia, a rickettsia-like bacteria)

Anaplasmas (related to the genera Rickettsia and Ehrlichia)


Babesia microti

Babesia WA-1



Bartonella henselae (cat scratch fever)

Bartonella quintana (trench fever)

Viral Meningitis

* * * * * * * * * * * * * * * * * * * * * * * * *

? POST-POLIO SYNDROME (PPS) & "Non-Paralytic" Polio

PCR Biopsy - An antibody test is not useful since it can not differentiate between an active infection, reactivated infection or antibodies from polio vaccines. However, a PCR test can be done on biopsied tissue and examined under a microscope to determine if there new polio virus or reactivated polio virus. Other viruses associated with PPS and NPP to test for:

ECHO viruses

Enteroviruses 71

Coxsackie virus A7 ("Polio virus Type IV")

Coxsackie B viruses (1-6)

* * * * * * * * * * * * * * * * * * * * * * * * *


1. INDIVIDUAL: The most accurate of the PCR blood tests is the individual test for a specific species.

2. "MULTIPLEX": Multi-species ("3 in 1" or "4 in 1") mycoplasma PCR blood tests are less expensive but their accuracy rate may not be as high as individual species tests. Therefore, patients need to specifically ask the laboratories for the published accuracy rate of their "multiplex" tests. Additionally, some laboratories identify a combination of tests for one price as a "panel" when in fact they are performing a "multiplex" test.

3. ANTIBODY TEST: The least accurate of the blood tests. In the case of Mycoplasma fermentans (incognitus), antibodies are not produced until the patient is near death. However, antibodies to the other mycoplasma species are produced more readily.

4. CULTURE: Mycoplasmas are rarely successfully cultured, as they require specialized culture mediums and weeks of careful laboratory work. In some rare instances, culturing may be an alternative choice.

* * * * * * * * * * * * * * * * * * * * * * * * *


— Do not perform the General (or Family) Mycoplasma species screening test. It is not as accurate as hoped. This test should never be used by physicians as a screening test for mycoplasmal infections in patients.

— Have the blood drawn at the testing lab. If that is impractical, the second best solution is to have the blood delivered to the lab within 24 hours. Blood samples left at room temperature for longer than 24 hours cause half the mycoplasmas to die and disintegrate. After 72 hours at room temperature all the mycoplasmas will have died and disintegrated. Once they disintegrate, the specific genetic sequences needed for PCR amplification will have vanished, resulting in a false negative.

— Have the blood sample drawn later in the day if you are shipping overnight. This shortens the hours before the sample is processed. Also, have the blood drawn early in the week rather than on a Friday so that the sample arrives on a day when the lab is open, rather than sitting unprocessed over the weekend.

— Ship blood samples with small packs of blue ice which keeps the sample at a refrigerated temperature (not frozen). Place some packing material between the blood sample and the blue ice to prevent the blood from freezing, which causes coagulation, ruining the sample for testing.

— Do not take any antibiotics at least one month or longer before a PCR blood test. The antibiotics will remove most of the infection from the blood, reducing the chances of amplifying the specific genetic sequences needed for an accurate result.

— Do not take vitamins, herbs or supplements that boost the immune system and/or kill mycoplasmas. Examples would be colloidal silver, flax seed oil, fish oils, vitamin C, IP6, immune boosters, garlic, transfer factor, olive leaf extract, etc. Unfortunately, no research exists to guide patients on how long they should avoid these products before drawing blood.

— The best time to have blood drawn is when the patient is symptomatic. Mycoplasmas can become dormant from time to time, so if a patient is feeling well it might not be the best time to test.

— If patients receive a negative result, but are still symptomatic, they should consider being retested. Review our recommended testing procedures to see if they were followed correctly. Discuss the merits of retesting with your physician.

— Patients should never begin antibiotic treatment before being tested for a mycoplasmal infection. Some patients start antibiotics before being tested to see if they will show improvement. If they improve, they often refuse to stop using antibiotics before taking a PCR test due to relapses. Unfortunately, once antibiotics are started, the risk increases for getting a false PCR result, even if the patient stops taking antibiotics later. This leaves patients unsure of their exact infection, preventing them from taking the most effective antibiotic. Without a positive test result, physicians often refuse to prescribe long term antibiotics.

— Antibody Tests may be an alternative to PCR for patients already on antibiotics. Although traditional antibody tests are generally not as accurate as PCR, detection may be possible if a patient has developed mycoplasma antibodies.

* * * * * * * * * * * * * * * * * * * * * * * * *


North American: Canada

The Hospital for Sick Children

555 University Avenue

Toronto, Ontario, Canada M5G 1X8

Tel: 416.813.1500

The Molecular Microbiology Laboratory

Director: Dr. Raymond Tellier

Tel: 416.813.6592


Resource Technologist: Grant Johnson

Tel: 416.813.6139


Mycoplasma testing:


North America: United States of America

Clongen Laboratories, LLC * NEW LABORATORY *

Middlebrook Tech Park

12321 Middlebrook Road, Suite 120

Germantown, Maryland 20874

Toll Free: 877-CLONGEN

Tel: 301.916.0173

Fax: 301.916.0175


Email A. Kilani, Ph.D., MT(ASCP),President:


Mycoplasma Testing Services:

Medical Diagnostic Laboratories

133 Gaither Drive, Suite C

Mt. Laurel, New Jersey 08054

Toll-free: 877.269.0090

Tel: 609.608.1696

Fax: 609.608.1667




Mycoplasma tests:

Lyme tests:

The Arthritis Research Center

504 E. Diamond Avenue

Suite I Gaithersburg, Maryland 20877

Tel: 301.216.1231

Fax: 301.216.0302

(Mycoplasma PCR and Antibody tests)

Immunosciences Lab., Inc.

8693 Wilshire Blvd., Suite 200

Beverly Hills, California 90211

Toll-free: 800.950.4686

Tel: 310.657.1077

Fax: 310.657.1053



Mycoplasma tests:

Lyme Disease, Immunology of


W229 N1870 Westwood Drive

Waukesha, Wisconsin 53186

Toll-free: 888.589.6974

Tel: 262.446.0700

Fax: 262.446.0600



Mycoplasma multiplex test:

Quest Diagnostics Incorporated

One Malcolm Ave.

Teterboro, New Jersey 07608

Toll-free 800.222.0446

Tel: 201.393.5000

Fax: 201.462.4715


Mycoplasma test menu:

Contact Customer Service:

Laboratory Corporation of America Holdings (LH)

358 S. Main St.

Burlington, North Carolina 27215

Tel: 336.584.5171

Fax: 336.436.1205


Mycoplasma tests:

Focus Technologies, Inc.(Corporate Office)

13665 Dulles technology Drive, Suite 200

Herndon, Virginia 20171 USA

Tel: 703.480.2500

Fax: 703.480.2670


Mycoplasma tests:

Focus Technologies, Inc., (Cypress Laboratory)

5785 Corporate Avenue

Cypress, California 90630

Toll-free: 800.445.0185

Tel: 714.220.1900

Fax: 714.220.9213


Mycoplasma tests (click on "Test Listing" and then the letter "M":

Specialty Laboratories, Inc.

2211 Michigan Ave.

Santa Monica, California 90404-3900

Toll-free: 800.421.4449

Tel: 310.828.6543

Fax: 310.586.7275



Mycoplasma tests:

Esoterix Infectious Disease Center

7540 Louis Pasteur Dr # 202

San Antonio, Texas 78229

Toll-free: 800.299.7350 or 800.661.4118

Toll-free: Client Services: 800.383.0980

Tel: 210.614.7350, 210.614.7350

Fax: 201.692.1411, 210.614.7355


(staphylococcus and mycoplasma tests)

Caring Medical Rehabilitation Services

715 Lake Street, Suite 600

Oak Park, IL 60301

Tel: 708.848.7789

Fax: 708.848.7763



Mycoplasma tests:

DSI Medical Laboratories

Main Office, Billing and Test Results

12700 Westlinks Drive

Fort Myers, FL 33913

Toll-free: 888.DSI-LABS

Tel: 239.561.8200

E-mail: Infectious Disease


Mycoplasma tests:


Brigham and Women's Hospital

75 Francis Street,

Boston, MA 02115, USA

Tel: 1.617.732.5500, 1.617.732.6458

Patients requesting an appointment:1.800.BWH.9999

BWH affiliated doctor: 1.800.BWH.9999

Lab Home Page. Department of Pathology: Clinical Laboratory Division. Mycoplasma PCR tests:

IBT Reference Laboratory

10453 West 84th Terrace

Lenexa, KS 66214

Toll-free: 800.637.0370

Fax: 913.492.7145



("Marshall Protocol" Vitamin D) C3a and C5a Test

Chlamydia pneumoniae DNA Test

Mycoplasma pneumoniae DNA Test

St. Louis Children's Hospital

One Children's Place

St. Louis, Missouri 63110 USA

Tel: 314.454.6000

Virology Lab

Supervisor, Bill Mulford

Tel: 314.454.6039,

Director, Gregory Storch, MD

Tel: 314.454.6079

Mycoplasma tests:

IGeneX Inc.

797 San Antonio Road

Palo Alto, California 94303

Toll-free: 800.832.3200

Tel: 650.424.1191

Fax: 650.424.1196



Lyme & co-infections PCR tests:

Laboratory for the Diagnosis of Tick Borne Diseases

University Hospital L3-700

Stony Brook University Medical Center

Stony Brook, New York 11794-7300


Lyme Disease-Borrelia burgdorferi: ELISA, Western Blot, Immunoblot Babesiosis:IFA(HGE&HME antibodies), Western Blot, Immunoblotting, Blood Smear Ehrlichiosis:IFA(HGE&HME antibodies),Western Blot,Immunoblotting, Blood Smear, PCR Laboratory for the Diagnosis of Tick Borne Diseases Tel: 631.444.2375 Tick Identification Services Tel: 631.444.3744 Technical Service Tel: 631.444.7965 Marc Golightly,Ph.D., SI(ASCP)Director/Head

Tel: 631.444.2240



Bowen Research and Training Institute, Inc

P.O. Box 627

Palm Harbor, Florida 34682

Tel: 727.937.9077

Fax: 727.942.9687


Lyme tests:

Boston Biomedica Inc.

BBI Diagnostics Customer Service - USA

375 West Street

West Bridgewater, MA 02379

Toll-free: 800.676.1881

Tel: 508.580.1900 BBI

Fax: 508.508.2202



Lyme tests:

Nelson Medical Research Institute (Lyme Disease)

11664 Martin Rd.

Warren, MI 48093

Lida Mattman, Ph.D.:

Tel: 810.755.6430

Fax: 810.755.4511


1210 NE Windsor Drive

Lee's Summit, MO 64086

Toll-free: 800.305.5198

Fax: 816.347.0143



HHV-6a virus test:



Pontbeek 61

B-1731 Zellik,Belgium

Tel: 32.2.481.5310

Fax: 32.2.481.5311



Mycoplasma & co-infections PCR tests &

RNAP (RNase L Test in PBMC's):

Pro Health Laboratorium

Schoutlaan 4a

6002 EA Weert

The Netherlands

Tel: 31.0.495.545000

Fax: 31.0.495.550722


Micropathology Ltd.

University of Warwick Science Park

Barclays Venture Centre

Sir William Lyons Road

Coventry CV4 7EZ, United Kingdom

Tel: +

Fax: +



Mycoplasma tests:

Nutri-Link Ltd.

8A Powderham Road

Newton Abbot, Devon

TQ12 1EU, England

Tel: +

Fax: +

[U.K. representative of Immunosciences Lab., Inc.

Sends blood to Beverly Hills, CA USA]


Institute of Biotechnology

Laboratory of Immunology

V. Graiciuno 8

2028, Vilnius, Lithuania

Tel: 370.5.2602103

Fax: 370.5.2602116


Web Site:

Mycoplasma tests: Detection of mycoplasma infection by PCR


SRL Ranbaxy

Clinical Laboratory Testing

Mumbai, India

Toll Free Tel: 1.600.222.333

Customer care Group of SRL:

Tel: 022.5692.7333, 022.5690.1810

Tel: 022.5690.3851-61, Ext. 203, 216



Mycoplasma tests PCR:


Australian Biologics Testing Services

6th Floor Fayworth House

383 Pitt Street

Sydney NSW 2000, Australia

Tel: 61.2.9283.0807

Fax: 61.2.9283.0910


Australian Rickettsial Reference Laboratory

Director and founder: Dr Stephen R. Graves

The Geelong Hospital, Barwon Health, Bellarine

St, Geelong VIC 3220, Australia

Tel.: +61.3.5226.7552

Fax: +61.3.5226.7940



* * * * * * * * * * * * * * * * * * * * * * * * *


Hypercoagulation tests:

Hemex Laboratory

2505 West Beryl Avenue

Phoenix, Arizona 85021-1461

Toll-free: 800.999.CLOT (2568)

Tel: 602.997.9161

Fax: 602.997.1406



Rickettsia test:

Laboratory of Dr. Cecile Jadin

Postnet Suite 182

Private Bag X3

Northriding, 2162

Johannesburg, South Africa

Tel: + 27.11.460.1670

from 06.30am - 07.00am and

from 06.30pm - 07.00pm (local time)

Fax: + 27.11.794.3370



Candidiasis tests (Candida Immune Complexes #323):

AAL Reference Laboratories, Inc.

1715 E. Wilshire # 715

Santa Ana, CA 92705

Toll-free: 800.522.2611

Tel: 714.972.9979

Fax: 714.543.2034



Great Smokies Diagnostic Laboratory/Genovations™

63 Zillicoa Street

Asheville, North Carolina 28801

Toll-free: 800.522.4762

Tel: 828.253.0621

Fax: 828.252.9303



Helicobacter Pylori tests:


Clostridium difficile tests:


Ciguatoxins Test:

Dr. Yoshitsugi Hokama

Department of Pathology

University of Hawaii at Manoa,

Biomedical Science Room D-105

1960 East-West Road

Honolulu, HI 96822

Tel: 808.956.5464 messages may be left

Tel: 808.956.8682 direct line to the laboratory

Physicians only may email Dr. Hokama at

Paraoxonase - Genetic trait (PON1 enzymes)

(sarin gas and organophosphate pesticides exposures)

Robert Ware Haley, M.D.,

Gulf War Associated Illnesses,

The University of Texas Southwestern Medical Center at Dallas 5323 Harry Hines Boulevard, Dallas, Texas 75390.

Tel: 214.648.3111


IBT Reference Laboratory ("Marshall Protocol" Vitamin D C3a test) 10453 West 84th Terrace Lenexa, KS 66214

Toll-free: 800.637.0370

Fax: 913.492.7145



("Marshall Protocol" Vitamin D) C3a and C5a Test

Chlamydia pneumoniae DNA Test

Mycoplasma pneumoniae DNA Test

Quest Diagnostics ("Marshall Protocol" Vitamin D C3a test)

One Malcolm Avenue

Teterboro, NJ 07608

Toll-free: 800.222.0446

Tel: 201.393.5000


To Find a Quest Patient Service Center near you:

"Patient Service Centers Locator" On-Line:

"Patient Service Center Locator" Tel.: 800.377.8448

Specialty Laboratories ("Marshall Protocol" Vitamin D C3a test) 2211 Michigan Avenue Santa Monica, CA 90404-3900

Toll-free: 800.421.7110

Tel: 310.828.6543

Fax: 310.828.6634


Client Services:


Toll-free: 800.421.4449

Fax: 310.586.7275

Specialty Labs info on C3a testing

* * * * * * * * * * * * * * * * * * * * * * * * * * * * * *

© Copyright Sean & Leslee Dudley 2005. All rights reserved. Mycoplasma Registry for Gulf War Illness & Chronic Fatigue Syndrome, an unincorporated nonprofit association, California Reg. No. 6679. Contents of Mycoplasma Registry Reports, brochures, booklets and forms is the intellectual property of Sean & Leslee Dudley. Any copying, re-publication, re-distribution or re-posting on email lists or websites of complete or partial contents of any content used on this site, including by framing or similar means, of Mycoplasma Registry Reports, brochures, booklets and forms is expressly prohibited without the prior written consent of: Sean & Leslee Dudley MYCOPLASMA REGISTRY for gulf war syndrome & chronic fatigue syndrome We are unable to answer inquiries concerning this brochure.

News & Reports email lists:

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